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Course info KVM / 0IHM2 : Course description

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Department/Unit / Abbreviation	KVM / 0IHM2			Academic Year	2023/2024
Academic Year	2023/2024
Title	Haematological Examination Methods 2			Form of course completion	Exam
Form of course completion	Exam
Accredited / Credits	Yes, 6 Cred.			Type of completion	Oral
Type of completion	Oral
Time requirements	lecture 28 [Hours/Semester] practical class 42 [Hours/Semester]			Course credit prior to examination	Yes
Course credit prior to examination	Yes
Automatic acceptance of credit before examination	No
Included in study average	YES
Language of instruction	Czech
Occ/max				Automatic acceptance of credit before examination	No
Summer semester	13 / 13	0 / 0	0 / 0	Included in study average	YES
Winter semester	0 / -	0 / -	0 / -	Repeated registration	NO
Repeated registration	NO
Timetable	Yes			Semester taught	Summer semester
Semester taught	Summer semester
Minimum (B + C) students	not determined			Optional course	Yes
Optional course	Yes
Language of instruction	Czech			Internship duration	0
No. of hours of on-premise lessons				Evaluation scale	A|B|C|D|E|F
Periodicity	every year			Evaluation scale for credit before examination	S|N
Specification periodicity				Fundamental theoretical course	No
Fundamental course	Yes
Fundamental theoretical course	No
Evaluation scale	A|B|C|D|E|F
Evaluation scale for credit before examination	S|N
Substituted course	KVM/HEVM2
Preclusive courses	N/A
Prerequisite courses	KVM/0IHM1
Meet all prerequisites before registering			NO
Informally recommended courses	N/A
Courses depending on this Course	N/A
Histogram of students' grades over the years: Graphic PNG ,  XLS

Course objectives:
Clinical haematology is a discipline focused on diagnosis and therapy of blood diseases and haemotogenous organs. Haematologists study morphology of blood cells, their origination and maturation, distribution in various tissues of the organism, physiological function and also disorders, which stem in haemotogenous tissue or affect it. When studying these processes haematology interferes with many other medical branches - immunology and immunohaematology, internal medicine, oncology, pathology etc. In the course clinical haematology current perspective of physiology and pathophysiology of haematogenesis including anaemias, benign and malignant disorders of haemotogenous organs and lymphatic system, haemostasis, haemocoagulation and fibrinolysis are introduced. Haematological examination methods are components of paraclinical laboratory disciplines. They are focused on examination of properties of individual components constituting full blood and examination of haematogenous organs' status. Determination of values of the blood count including differential leucocyte calculation means determination of several tens of parameters by modern automated analyzers. Morphological evaluation of cells in peripheral blood and bone marrow including cytochemical examinations is a part of these examinations. As necessary they are completed by examination of functional status of individual blood elements. Haemocoagulant examinations check blood clotting and ability to dissolve blood clots that have been formed. Basic knowledge of the principle and construction of a measurement laboratory technology and application of computer technology and computer science in laboratory daily routine are necessary.
Requirements on student
Conditions for obtaining the exam: 1. Exercise: - participation in exercises: 100 %, - submission of all protocols from practical exercises, - successful mastering of the final interpretation of laboratory findings, - credit test (min. success rate 70 %). 2. Lectures: - participation in lectures: 80 %, - a short presentation (8-10 minutes) on a selected topic. The course ends with an oral exam.
Content
Lecture: Congenital and acquired coagulopathy: definition, classification, diagnosis, differential diagnosis and therapy, case reports Seminar.: Haemocoagulation screening tests I, case reports Lecture.: Thrombophilia states: definition, classification, diagnosis and therapy review, case reports Seminar.: Haemocoagulation screening tests II, case reports Lecture.: Thrombo hemorrhagic syndromes: definition, classification, diagnosis, differential diagnosis and therapy, case reports Seminar.: Special I Haemocoagulation examination tests, case reports Lecture.: Thrombo hemorrhagic syndromes: definition, classification, diagnosis, differential diagnosis and therapy, case reports Seminar.: Special Haemocoagulation Tests examination, case reports Lecture The most common findings in practice, non-specific reactive changes in blood count and basic coagulation tests: diagnosis and differential diagnosis Seminar.: The most common findings in practice, non-specific reactive changes in blood count and basic coagulation tests: diagnosis and differential diagnosis Lecture.: Rules for interpretation of results of basic haematological (blood count and coagulation tests), case reports, cytochemical staining methods. Seminar.: Staining of blood smears and bone marrow - basic and special staining methods Lecture.:.: General rules of diagnosis and treatment of cancer and blood forming organs Seminar.: Cytological evaluation of physiological bone marrow coatings Lecture Myelodysplastic syndrome: definition, classification, diagnosis, differential diagnosis and review therapy, case reports Seminar.: Cytological evaluation of peripheral blood smear and bone marrow iron staining and interpretation of results, the importance of flow cytometry and histological evaluation of bone marrow, case reports Lecture.: Acute leukemia: definition, classification, diagnosis, differential diagnosis and review therapy, case reports Seminar.: Cytological evaluation of peripheral blood smear and bone marrow, the importance of flow cytometry and histological evaluation of bone marrow, case reports Lecture.: Myeloproliferative diseases of hematopoiesis: definition, classification, diagnosis, differential diagnosis and review therapy, case reports Seminar.:.: Cytological evaluation of peripheral blood smear and bone marrow, the importance of flow cytometry and histological evaluation of bone marrow, case reports Lecture.: Lymphomas: definitions, classification, diagnosis, differential diagnosis aterapie, case reports Seminar.: Cytological evaluation of peripheral blood smear and bone marrow, the importance of flow cytometry and histological evaluation of bone marrow, case reports Lecture.: Chronic lymphocytic leukemia and related units: definition, classification, diagnosis, differential diagnosis and therapy, case reports Seminar.: Cytological evaluation of peripheral blood smear and bone marrow, the importance of flow cytometry and histological evaluation of bone marrow, case reports Lecture.: Multiple myeloma and other monoclonal gammopathy: definition, classification, diagnosis, differential diagnosis and therapy, case reports Seminar.: Cytological evaluation of peripheral blood smear and bone marrow, the importance of flow cytometry and histological evaluation of bone marrow, case repor Lecture.: Transplantat of hematopoietic stem cells Seminar.: Blood Parasites
Activities
Fields of study
Guarantors and lecturers
Guarantors: Ing. Martin Pulcer, Ph.D., MBA ,  Lecturer: Ing. Martin Pulcer, Ph.D., MBA (100%),  Tutorial lecturer: Mgr. Soňa Kolářová (50%),  Mgr. Lucie Recová (50%),
Literature
Basic: Indrák Karel a kol. Hematologie. Triton, Praha, 2014. ISBN 978-80-7387-722-4. Basic: Fáber Edgar et al. Základy hematologické diagnostiky. 2. vydání. Mladá fronta, 2015. ISBN 978-80-204-3742-6. Basic: Matuška Milan. Základy onkolologické hematologie pro zdravotní laboranty. Ostravská univerzita v Ostravě, 2015. ISBN 978-80-7464-597-6. Extending: Pulcer M. a kol. Hematologie pro zdravotní laboranty I. Ostrava, 2022. ISBN 978-80-7599-322-9. Extending: Škorňová I., Slavík L. a kol. Hemostáza. Turany, 2020. ISBN 978-80-89694-78-5. Extending: Haferlach, T. Kapesní atlas hematologie. Havlíčkův Brod, 2014. ISBN 978-80-247-4787-3. Extending: Penka Miroslav a Alena Bulíková a kol. Neonkologická hematologie. Praha, Grada, 2009. ISBN 978-80-247-2299-3. Recommended: Penka M. a kol. Hematologie a transfúzní lékařství I. Praha, 2011. ISBN 978-80-247-3459-0. Recommended: Vydra J. a kol. Hematologie v kostce. Praha, 2023. ISBN 978-80-88506-13-3. Recommended: Kačírková, P., Campr, V. Hematoonkologický atlas krve a kostní dřeně. Grada, 2007. ISBN 978-80-247-1853-8. Recommended: Dulíček Petr. Poruchy hemostázy v klinické praxi. Havlíčkův Brod, 2022. ISBN 978-80-271-3337-6. Recommended: Pecka, M. Praktická hematologie - Laboratorní metody. Český Těšín, 2010. ISBN 978-80-903871-9-5. On-line library catalogues
Time requirements
All forms of study Activities Time requirements for activity [h] Being present in classes 60 Preparation for an exam 60 Scientific text studying in the Czech language 10 Hand-out completion for the lesson 18 Preparation for a credit test 24 Total 172
Prerequisites
Learning outcomes
Knowledge - knowledge resulting from the course: The student will acquire advanced knowledge and skills in examination methodologies of special coagulation, cytological evaluation of peripheral blood circulation and bone marrow.
Assessment methods
Knowledge - knowledge achieved by taking this course are verified by the following means: IC6 - Oral examiantion
Teaching methods
Knowledge - the following training methods are used to achieve the required knowledge: A1 - Lecture C4 - Instruction C5 - Static and dynamic projection/presentation C2 - Demontration of obejcts/phenomena/processes D9 - Experiment